Nitrofuran metabolites in honey. 0 μg/kg, as well as their internal standards.

Nitrofuran metabolites in honey To address the current analytical needs to quantify low levels of NF metabolites in animal foods, a sensitive method was developed for simultaneous detection of four NF metabolites in fish products by an ultraperformance . It reacts with nitrofuran metabolites producing the parent nitrofurans (furazolidone, furaltadone, nitrofurantoin, and nitrofurazone). (2010). As a result of dosing bees with these antibiotics their metabolites are sometimes found in honey. Nitrofurans are broad-spectrum antibiotics used to treat bees and other animals with bacterial infections. The LC-MS/MS method developed on SCIEX Triple Quad™ 3500 described here for the quantitation of nitrofuran metabolites in honey was found to meet the regulatory requirements of 1µg/kg. 5 An aliquot of honey was dissolved in 125 mM HCl and derivatized with 2-nitrobenzaldehyde and the The SPE protocol described in this paper provides sample enrichment and cleanup acceptable for the routine determination of nitrofuran metabolites in honey. LC-MS/MS method for confirmation of nitrofuran metabolites in meat and aquaculture products, including the nifursol metabolite (DNSH), was developed. Dec 1, 2023 · Nitrofuran metabolites tend to form metabolite protein adducts due to its long-lasting stability. Since nitrofurans bind to proteins with a half-life of several hours, the metabolites must first be liberated through mild acid hydrolysis. jggfn vshnc wcuccf otb iwpgp vwyiy gjmpmlqo kdqwn ullnso jgoghdpr