Poe poison proliferation Enemy dies and this poison proliferates as the strongest one. Bleed, poison, and ignite are damaging ailments. 6) Phys+Chaos: (223. Minions cannot gain Cruelty. PROS: poison (because inc. Nature's Adrenaline 4. Finally, Waypoint back to The Vaal City, travel to Temple of Decay 2, and kill Arakaali. Spam Gas Arrow while moving to create overlapping poison clouds. PF poison proliferation; Heavily reduce enemy action speed with vines and temp chains. Whenever you apply poison it applies a new stack and refreshes the current or if each one is running it's on course? Also, how many times does each projectile of spectral throw hit exactly and can a single target be hit by multiple projectiles at the same time? For example, let’s take a pathfinder with poison proliferation and mastery or cluster node “poison on non-poisoned 300% inc damage”. By default, only lightning damage is able to inflict shock. Elemental Proliferation Support Cold, Fire, Lightning, Support, AoE Icon: S Level: (1-20) Cost & Reservation Multiplier: 110% Supports any skill that hits enemies, or could otherwise apply elemental ailments. The support gem ‘Ignite Proliferation’ has three tags - Fire, Support, and AoE. Walkthrough. You'll get faster ramp of poison damage, you'll be able to dip in and out of danger to attack with smaller opportunity windows, and you'll be able to react to danger faster by Whirling Blades away. Depends what you value more. 1. 4-248. Poison proliferation does not hit, but Poisonous Concoction does and will apply Temp Chains. 00)% Attacks per Second: 1. in/GGm-JshlroHF [3. Each application—or 'stack'—of poison remains present on the target dealing chaos damage over time until it runs its course. 5% chance to Ignite Ignites caused by Skill gem; Herald of Agony Herald of Agony Spell, Herald, Minion, Chaos, Physical Level: (1-20) Reservation: 25% Mana Cooldown Time: 1. A place to talk about POE builds, mechanics and interactions. This build uses a Lightning Spell Damage instead. Complete Build Guide on Poisonous Concoction Pathfinder which utilizes the new thrown projectile attack to deal massive Damage over Time with Poison It also grants you Poison Proliferation, Odealo is a player-driven marketplace for PoE Currency, Orbs, and Unique items. A key strategy for maximizing damage against bosses involves positioning your cursor closer to your character, exploiting Scourge Arrow's unique mechanics for optimal Mechanics. Also weird things like Armabrand poison can be really good because of the jumping brand (can pair that with ignite proliferation and blackflame ring), but that’s more of a meme theorycrafting Poison Proliferation from Bino's / Pathfinder appears to clone the highest damaging poison (I dunno if its by total dmg or dps, Im guessing total damage), and apply it to nearby enemies. 0. 25. You could take Gentle touch gloves + prolif from a fire dot cluster jewel (i dont remember if you also need herald of ash for it) Penance Brand and Pathfinder Poison Proliferation. 6) Total: (223. 16 that was unpopular. The modifiers in question also do not "spread poisons" (although the one on Binos used to say this in the past, in relation to an older version of it's A user asks how to spread poison for Herald of Ice build that uses brittle and elemental proliferation. Chill, freeze, shock, scorch, brittle, and sap are collectively referred to as non-damaging ailments. Our recommended setup uses no Unique jewels. 3- Keep close to the pump. That will lead to chain reaction. 24 no longer carries the label of a boss killer, it's adept at dispatching most non-uber bosses with ease. PoE 2 SSF Tier List - Best Solo-Self Found Class & Builds in Hardcore & Standard. When you poison an enemy while you have this buff, you gain Virulence, and summon an Agony It seemed to me that the body being destroyed by the explosion (which will be always) breaks the prolif chain, but with enough global poison chance the explosions can poison as well. It grants a chance for poisons applied during any flask effect to deal more damage. Proliferation is an effect that causes the spreading of an ailment from a dead target to another nearby enemy. Simply hit a worm with 100% chance to poison/ignite and using the golden rule (for poison at least) I can confirm that the definately do receive the poison but will not spread it on death to nearby enemies regardless if it's a another worm or not. Lots of room for improvement and optimizations still. Build's PROS & CONS. . Anything that affects those three tags, ie Increased Fire Damage, Increased level of Support gems, etc, will affect this gem. Per 1% Quality: 1 Superior 2 Anomalous 3 Divergent 0. 00 sec Can Store 1 Use(s) Cast Time: Instant Requires Level 16 Grants a buff giving more poison damage and a chance to inflict poison. 5% increased Fire Damage Supported Skills have 0. Poison is a cumulatively stacking debuff. Ignite, chill, freeze, shock, scorch, brittle, and sap are collectively referred to as elemental ailments. Explore the best, most effective, and downright broken PoE 2 builds. The poison proliferation makes clear amazing. Everything will get hit at least once before they die to poison, so there will be plenty of cursed corpses to proc the glove explode. Nearby enemies affected by these auras do not gain the Elemental Proliferation Support Cold, Fire, Lightning, Support, AoE Icon: S Level: (1-20) Cost & Reservation Multiplier: 110% Supports any skill that hits enemies, or could otherwise apply elemental ailments. Nearby enemies affected by these auras do not gain the auras, because only a target that has received a status ailment – as a result of being hit – can gain them. Cons: Profane Bloom + Poison Proliferation Theory Is there any point to pair this mechanics (with Bino knife) on a Low Tolerance stacker? In honor of alternate quality gems going away, I thought I'd re-share one of my all-time favorite PoE videos; Eirikeiken's "anti-support" build. Our Poison BV Assassin will carry you through the game in a breeze! in Path of Exile: As the build plays as an Assassin and thus has no proliferation for its poisons, If you need any help with his builds you can ask it on the PoE Vault Discord. A place to talk about POE builds, PSA: Lesser known source of Poison and Ignite Proliferation, Animate Guardian + Gravebind + Bino's + Abberath's Hooves Theory Just wanted to put this info out there in case people didnt know and want to experiment with sources of Poison or Ignite prolif for themselves or their minions. 4-2) metres Supported Skills deal (15-24)% more Damage with Ignite Bino's Kitchen Knife Slaughter Knife Rune Dagger Physical Damage: (150-165) to (296-321) Critical Strike Chance: (11. Master Surgeon (early game) / Nature's Boon (late game): Boost flask uptime and effectiveness. It also causes you to The result is an Assassin crit-based ED that ignores the inherent DOT from ED and instead scales the initial hit with tons of double dipping sources. Withers enemies, and Poison Proliferation. Maybe not to the strength of BA elementalist, but any build with Ignite Prolif works. Pick a damage type and color theme for example. Nessa: Lioneye's Watch isn't much, but it's ours. Pros and Cons Benefits Note that this Proliferation and chance to deal double poison damage does not affect Plague Bearer. Discussion . Get ascendancy points in this order: 1. Patch version. Skill gem. Portions of poisons inflicted by non-chaos damage are affected by modifiers that would increase the source damage type for the corresponding portion of the poison damage. (0-19)% increased Poison Proliferation would be a literal flag changing the gem to Poison damage. It just WALKS - My FaceTanking Juggernaut Build for AFK T17 farm, Poison Tornado Pathfinder Build Guide - Fun, Fast / All Content (2 Budget POB in comments) Usually, Poison is inflicted by dealing Physical or Chaos Damage. We need 4 different items in order to self-poison ourselves which will lead to chilling ourselves. 7 i see elemental proliferation is "cold, lightning, fire". 5% increased Area of Effect Supported Skills have 0. I've been a fan of poison build for some time and trying niche ways of building them. It spreads the single strongest Poison from the killed enemy to all nearby monsters. This percentage is affected multiplicatively by ailment effect/magnitude. Ranger 3. Silver Flask) ft. I think the most fun I had was in delirium league with the cobra lash dagger, back before the poison mod nerf. with poison damage of 10k, without duration, that means per poison, one is doing 5k poison damage. He has experience playing solo and both in push, while being notorious for his _World First Delve 6000_ with his team & farming multiple Mirrors of Kalandra every league. Most agree that pathfinder is the best option, with some tips on There is no proliferation of poison in PoE. The That's the point, if you have 100% base chance to poison (which is easy for assassin), then those physical explosion would apply poison as well, and after new poisoned monster die, they will also explode and apply poison too. 5% increased Duration of Elemental Ailments on Enemies Supported Skills have 1% increased Area of Effect Poison proliferation. But, should you wish to venture out, do just one thing for me? Out on the coast, amongst the wrecks, there must be a ship's Medicine Chest Medicine Chest Doctor "Shaky Hands" Opden Bino's Kitchen Knife Slaughter Knife Rune Dagger Physical Damage: (150-165) to (296-321) Critical Strike Chance: (11. Avoid the cone of Each build will be rated for leveling, mapping, and bossing, alongside detailed recommendations for PoE 2 skill gems, gear, passive trees, and gameplay tips. Ailment damage cannot be scaled directly; however, it can be indirectly scaled by modifying the hit damage. They can however receive ailments from proliferation but not spread it. These can be seen listed at the top of the gem information. 🔗 PoE forum post. Highlights. You could run a Watcher's Eye Blade Vortex. Huge damage, poison proliferation, whirling blades, and near infinite flasks make for great quality of life. Solo Self Found The build focuses heavily on poison proliferation, making it devastating in large-scale fights but requiring smart positioning and Item Base item Stats; Dendrobate Dendrobate Sentinel Jacket Evasion: (758-925) Energy Shield: (246-290) Movement Speed: -3% Requires Level 59, 86 Dex, 86 Int Socketed Gems are Supported by Level 10 Chance to Poison (130-150)% increased Evasion and Energy Shield +40 to maximum Energy Shield +(15-25)% to all Elemental Resistances (75-100)% Mechanics. Quick question: is Master toxicist poison proliferation affected by increases and reductions to area of effect? Help In honor of alternate quality gems going away, I thought I'd re-share one of my all-time favorite PoE videos; Eirikeiken's "anti-support" build. Talk to Nessa to start the quest. One of the very few limited ways to Poison with any type of damage is to wear the Inextricable Fate Boots, which until the 3. 9. The logic I was given for why proliferating elemental ailments doesn’t work, is that they require a corpse, but worms are destroyed, so they can’t proliferate. Also I can say that Cyclone is my favourite skill in game, Ignite Proliferation Support Fire, Support, AoE Icon: I Level: (1-20) Cost & Reservation Multiplier: 130% Requires Level 38 Supports any skill that hits enemies. Relive 3. Now I am using claws, dual wasp nests, and it’s clear is horrendous in comparison due to not having poison proliferation. Elemental proliferation is a modifier that makes hits apply status ailment debuffs as auras to targets; these debuff auras have the same effects and durations as the original debuffs. So you're trading true proliferation for corpse removal and (potentially) bigger poisons for grouped mobs ((like metamorphs)). Poison proliferation will quickly clear packs. duration scales both the duration of the Boneshatter buff and damage) pathfinder for poison proliferation and more damage from natures reprisal POB suggestions for uniques: +Replica Wings of Entropy (decent DPS, lots of AS, crit without investment for Unholy Might from Overwhelming Malice), +Dendrobate (for pseudo 7link), +Devoto's Devotion (AS) If you have any questions about the build or just want to talk you can always @ me in PoE Discord (my username is deathbeam). Last league I was also played Hollow Palm for the first time in my 6k+ hours in POE, but with Cyclone skill with DMG converted about 80% to fire. being you stack low tolerance cluster jewels and use a Bino's or pathfinder ascendancy to proliferate one big poison onto a boss from the penance mark phantasms. It will be very low investment for the amount of damage potential. The poison spreading is also not technically a proliferate. Killed all content up to and including end game bosses, but not tested against "aspirational" content such as 100% Delirious T17s. I played it and enjoyed it from league start all the way through Uber elder, Maven, etc up but didn't manage to take down the feared. Random level 20 support gem: A: 7: Dialla's Subjugation Dialla's Subjugation 7 Support Gem Quality: +23% Corrupted A symbol of beauty and innocence The gems Poison is an ailment that deals chaos damage over time to the affected target. 40 Weapon Range: 10 Requires Level 58, Damaging ailments. Supported Skills deal (15-24)% more Damage with Hits Cruelty has a Base Duration of 4 seconds TbXie has been playing Path of Exile since the release of Open Beta, playing a variety of leagues in which he has played Hard- and Softcore, Standard, and Solo-Self Found. tv/jungroanpathfinder is probably better honestly but raider fast6 portal uber sirus viablehttps://pobb. Acid molten strike assassin was the best poison build before 3. The most notable difference is that ailments are associated with damage To improve survivability with poison melee builds, you want a ton of defensive layers (depends on the class you pick), but a lot of people forget how important attack speed is to poison builds. Hello. If i use a cautious life flask while on low life, will this 130% more modifier persist when i reach non-low life? Ignite Proliferation Support Ignite Proliferation Support Fire, Support, AoE Icon: I Level: (1-20) Cost & Reservation Multiplier: 130% Requires Level 38 Supports any skill that hits enemies. Disclaimer: While this Poison Scourge Arrow Pathfinder build for Necropolis 3. 0 metres Requires Level 65, 81 Dex, 117 Int 30% increased Global Critical Strike Chance Adds (140-155) to (210-235) Physical Damage (40-50)% increased Critical Strike Chance +(15-25)% Zizaran made a poison spectral helix occultist build guide for 3. 2. Each curse debuff has default values, visible in the reminder text of stats which apply the curse. lol You're wrong. Posted by sevens67 on Dec 8, 2023, 3:34:29 AM. Master Toxicist 3. 25 patch almost no one did, because you first have to apply at least 3 Grasping Vines on an enemy, and there were no base duration of poison is 2 seconds. News 03 Dec Vendor Offer 7x Alchemy Shard 13x Alteration Shard Weapon DPS Physical: (223. This can be interesting in combination with The Golden Rule The Golden Rule Viridian Jewel Limited to: 1 (30-40)% increased Armour while Bleeding Bleeding you inflict is Reflected to you +1% to Chaos Resistance per Poison on you Poison Total damage per poison, which is how much damage the poison does over its complete duration (getting this number high is good for poison proliferation builds - pestilent strike) Total dps inc. Use Contagious Contamination from the Pathfinder Ascendancy to spread the Poison The Scourge Arrow Poison Pathfinder excels at dealing massive Single Target damage which it proliferates to clear entire screens. I was watching a streamer using Binos, and their poison proliferation was clearing more than a whole screen with one fling of their Cobra Lash. In general, curses are balanced so that a level 1 curse skill without quality applies the curse with the default values, and higher levels override them with higher Overall cwc poison dd is very strong and comfortable build to play, but i wouldn't go around saying this is a budget league starter build, you should leaguestart with another witch/occultist build then reroll into it once you've obtained some currency. What I always struggled with is the poison prolif and ways you can get it. Modifiers to chance to shock can be found on some gems, equipment, and the passive skill tree. Step 4. Ascendancy, Builds, Skills, Passives, Bossing & Mapping. If possible add a Meteor Tower with Burning Ground enchant. Fixed a bug where the Shock status spread by Elemental Proliferation would ignore the Shock limit. When applied by a skill, the skill overrides these default values. Browse Games. 30% Attacks per Second: 1. Elemental Proliferation is now affected by increases to Area of Effect. 25] Scourge Arrow Poison Prolif Pathfinder - Fast, tanky, fun to play By thedeathbeam. 👀 3170375 🗨️ 6999 ⌛ 5 months ago. Be sure to check out our Flask Crafting Guide to learn everything you need to know about how to set up your non-Unique flasks. Some skill effects and modifiers, such as Shocked If you have any questions about the build or just want to talk you can always @ me in PoE Discord (my username is deathbeam). 6) Metadata Item class: Rune Daggers Bino's Kitchen Knife is a unique Slaughter Knife Slaughter Knife Rune Dagger Physical Damage: 10-86 Critical Strike Chance: 6. But seriously though, there are so many other Curse proliferation . If not, there's ED/Contagion. Changelog Click here to view Pro's & Con's + Pretty good bossing with ballistas + Really good clear speed (because of Master Toxicist poison proliferation and Scourge Arrow coverage) + 200%+ increased movement speed It doesnt outperform assassin for poison because of prolif, it just prolif 1 single stack which is garbage damage. Nature's Boon. The build highly rewards you for investing in it, with very satisfying power spikes along the way. So this should work, especially with increased AoE. ↖ Gear Recommendations. Item Base item Stats; The Embalmer The Embalmer Carnal Mitts Evasion: (90-101) Energy Shield: (19-21) Requires Level 50, 39 Dex, 39 Int Socketed Gems are Supported by Level 20 Vile Toxins Adds (13-17) to (23-29) Chaos Damage +(50-70) to maximum Life +(17-29)% to Chaos Resistance (20-25)% increased Poison Duration "Decomposition takes hold too Yes, I did misuse the technical POE definition of proliferation. 7 Edit: If you want to play assassin and have some kind of "prolif" poison just use bino knife League started this build and it's quite impressive. Mechanics. If you can combine this kind of proliferation with corpse explosions then you have a chain reaction. Members Online. 9: Increased mana cost multiplier from 140% to 180%. As poison deals damage over time, stats modifying spell damage and attack damage do not apply Users share their opinions on the best "spreading" poison proliferation build for Path of Exile, a popular action RPG game. Cheap. Seems like it would be really good for lots more poisons! I just went slayer for the melee splash (and the memes). - Icefang Orbit | Causes poisons to chill (So you'll chill yourself) - Winterweave | Reverses chill efect (Free MS and AS) - Maw of Conquest | Unaffected by Poison (So you'll not insta-die to 100 poison stacks) The Playstyle is very satisfying thanks to the Poison proliferation provided by the Pathfinder Ascendancy. And now that the Holy Conquest mechanic is available as a mastery, Wintertide Brand is a possible candidate; Storm and Arma Brands can also jump but they're a lot less dependent on the pseudo-prolif of the old Holy Conquest than something like Wintertide or Pestilent Strike (Poison Proliferation, but only 160% damage effectiveness) I'm pretty sure this is not that big of a deal with stronger gear, but some build paths are just dead now. Poison proliferation w/ Bino's Kitchen Knife Master Toxicity: Enable poison proliferation and boost poison damage. Bleeding, poison, and ignite are damaging ailments. This Mark creates a Caustic Ground based on the single Poison applied to the enemy, in a similar fashion to Burning Ground created by Flame Surge used on Ignited enemy. Other sources of DoT multiplier that apply to ailment DoT multiplier, including generic and conditional DoT multiplier bonuses, will be ignored. Poison deals 20% of a hit's combined physical and chaos damage dealt (before mitigation and damage taken modifiers) as chaos damage over time per second for 2 seconds. Nature's Reprisal 2. Pneumatic Dagger poison builds are really crazy because "increased elemental damage with attacks" mods work on the poison, since it's coming from elemental damage. https://www. Unique item. poison, which is a little misleading because of all the bonuses you get for recent attacks, but in general a larger number here is better. But The poison proliferation from Nature's Reprisal Pathfinder Ascendancy: "When you kill a Poisoned Enemy during any Flask Effect, nearby Enemies are Poisoned" don't work with the Explosion mod from the Crusader Chest: "Enemies you Kill Explode, dealing 3% of their Life as Physical Damage" She enables you high flask up time, pushes further clear speed thru proliferation of the poison, scales well poison itself. So, I figured I might as well Poison concoction or toxic rain until you can make the change. -the best kind of Proliferation is global proliferation (gloves / cluster jewel). ninja, in Expedition it was at 50%. Ailments are in many ways similar to debuffs. I really wanted to juice up the poison duration and starting at 4 seconds (Viper Strike) and allowing skill effect duration and the helm enchant to scale the duration was what I PoE 2 Best Gemling Legionnaire Build The combination of massive AoE damage through Poison Proliferation, powerful single-target capabilities with Bleed, Poison, and Armor Break, and robust tankiness from Strength stacking and Stun Immunity, With each release, you will be applying multiple Poison stacks on enemies all around your screen, with the extra Poison "proliferation" from Pathfinder's Ascendancy, you will see enemies melt all over your screen after each Hit, and with high Attack Speed, this build will feel swift and mobile, even though you need to be stationary while First t16 guardian map. For assassin the most obvious poison theme would be poison, daggers, and critical strikes. 22 Ancestor League. We could use you here, while you live. However, contrary to the standard proliferation mechanics, poisons are reapplied instantly Poisonous Concoction is a skill that throws your mana flask at monsters to poison them. 📺 10 videos found. It relies on stacking Poisons on enemies Moderately zoomy, can be faster with a sacrifice in dps/damage (eg. Ignites caused by Supported Skills spread to other Enemies within (1. Hexblast / Impending Doom can be very good too. Open maps spawn to many lanes and shit gets crazy. 40 Weapon Range: 1. 2- Ice Towers + Stun Towers with ring enchants to perma-stun everything. One of my personal favorite builds of all time, Poison BV is back in the game after a sleuth of buffs to self-casting, which in turn amps up Poison Damage, and with Ashes of the Star (if you're rich, that is), Cruelty is a buff associated with Cruelty Support Cruelty Support Support, Duration Icon: Y Level: (1-20) Cost & Reservation Multiplier: 140% Requires Level 18 Supports any skill that hits enemies. Vixen's Entrapment: Enables multiple curse application and triggers Impending Doom explosions. You can still have character identity/fantasy, just don't use attributes as the basis, it's unimaginative anyways. 0 metres Requires Level 65, 81 Dex, 117 Pathfinder Poison Tornado Shot Elementalist Ignite Proliferation Firestorm Some general rules for Blight: 1- Do it in closed maps. Rare Jewels. Per 1% Quality: 1 Superior 2 Anomalous 3 Divergent Supported Skills deal 0. 23 but with a nerfed version of Affliction (rip). 20-12. GGG has confirmed that the ability to use Poison Proliferation from the penance phantasms is 100% possible and supported. Offscreen also comes from proliferation. Comprehensive guides on skill gems, playstyle, items and more. Build Overview. Question regarding the following mechanics: If i use the inextricable fate as a pathfinder, and poison an enemy with my fire damage after waiting for 1. Crit Poisonous Concoction Eye of winter. I prefer to play both as a pathfinder. We poison first enemy with first poison which deals 300 inc damage (simplifying). This item causes your poison debuffs to inflict a base 10% chill, affected by chill and ailment modifiers. Noxious and Toxicity would have similar characteristics to F&S while there the same 25% mana reservation cost but with a sort of twist, Noxious would give 'Poisons you inflict deal Damage 20% faster, 10% Less Poison Damage' while Toxicity would give 'Poisons you inflict deal Damage 20% slower, Amount Part Description Meta; 9: Gift of the Gemling Queen Gift of the Gemling Queen 9 Level 20 Support Gem Our Lady Dialla, as a symbol of our progress, shines greater than all the gems. 5 seconds, will this poison spread to other enemies that do not have grappling vines on them due to poison proliferation?. Ranged playstyle, great with shrines (and probably inspired learning too if I could fit it in). Fortify is at 14% usage on Dom Blow builds on poe. Critical strikes always inflict shock regardless of their chance to shock. Another thing that works greatly with this playstyle is Pathfinder's Poison Proliferation. increasing duration by 100% means duration of 4 seconds - yes, dps has not increased, but that means total damage per poison is now 20k. 11g: Fixed a bug where Elemental Proliferation would not work with Freeze Mine. Other users suggest Bino's or Pathfinder as the only ways to proliferate poison, + Really good clear speed (because of Master Toxicist poison proliferation and Scourge Arrow coverage) + 190% + increased movement speed + 100% spell suppression Master Toxicist is a notable Ascendancy passive skill for the Pathfinder. A hit of damage that has a X% chance to shock is capable of inflicting shock. Changelog Click here to view Pro’s & Con’s + Pretty good bossing with ballistas + Really good clear speed (because of Master Toxicist poison proliferation and Scourge Arrow coverage) + 190%+ increased movement speed + 100% spell An ailment is a detrimental effect associated with one or more damage types. twitch. A hit of damage that has a chance to poison is capable of inflicting poison. Only physical and chaos damage are able to inflict poison. Damage over Time Multiplier for Ailment is equal to Critical Strike Multiplier: Perfect Agony will override your DoT multiplier with ailments to be equal to your critical strike multiplier. The remaining ailments, Chill, freeze, shock, scorch, brittle, and sap, are non-Damaging Ailment s. Damaging Ailments are ailments that deal damage over time. Nature's Adrenaline: Enhance flask sustain and usability. Character class. Elemental proliferation is a modifiers that makes hits apply status ailment debuffs as auras to targets; these debuff auras have the same effects and durations as the original debuffs. So, second enemy takes this full damage, but it’s non But as far as normal builds go, Scourge Arrow is a great starter and Lightning Strike (with a pneumatic dagger) is very good with some decent gear. WED scales any elemental damage your weapon does, but for puncture it will not scale the damage over time effect, the bleed, because bleed does a % of your Physical damage over time. Poison Spark Pathfinder Endgame Build Guide for Path of Exile 3. When you kill Elemental proliferation. Best of all, 4 Utility Flasks will be permanently active at higher percent effect than Mageblood, saving wrist pain and enabling Pathfinder’s poison proliferation on enemies to be a permanent and effortless effect. Contagion is not present at all The secondary effect of this passive is often referred to by the community as "poison proliferation". The possibilities for builds and character fantasy in PoE are practically endless. this alone is helpful as it has not expedited the death of the shaper guardian directly, but has made Mercy Mission is an optional quest in Act 1. Curses are a type of debuff. When is that change? I don't know, I play PoB not PoE. It's very easy to test this.